The skin barrier in healthy and diseased state.

@article{Bouwstra2006TheSB,
  title={The skin barrier in healthy and diseased state.},
  author={Joke A. Bouwstra and Maria Ponec},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1758 12},
  pages={2080-95}
}
The primary function of the skin is to protect the body for unwanted influences from the environment. The main barrier of the skin is located in the outermost layer of the skin, the stratum corneum. The stratum corneum consists of corneocytes surrounded by lipid regions. As most drugs applied onto the skin permeate along the lipid domains, the lipid organization is considered to be very important for the skin barrier function. It is for this reason that the lipid organization has been… CONTINUE READING