The "sins" of the fathers: self-healing squamous epithelioma in Scotland.


BACKGROUND A review is presented of the recent progress made in mapping of the hereditary skin disease "Ferguson-Smith multiple self-healing squamous epithelioma." METHODS The use of founder effects in an autosomal dominant disease is reviewed as applied to gene mapping efforts. RESULTS A common haplotype among Scottish families segregating Ferguson-Smith disease allowed the narrowing of the candidate gene interval and the identification of several possible disease-associated genes. CONCLUSION The gene for Ferguson-Smith multiple self-healing squamous epithelioma lies in a narrow region on chromosome 9q, along with several other important hereditary skin disease loci.

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@article{Bale1999TheO, title={The "sins" of the fathers: self-healing squamous epithelioma in Scotland.}, author={Sherrie J. Bale}, journal={Journal of cutaneous medicine and surgery}, year={1999}, volume={3 4}, pages={207-10} }