The single substance and mixture toxicity of quinolones to the bioluminescent bacterium Vibrio fischeri.

@article{Backhaus2000TheSS,
  title={The single substance and mixture toxicity of quinolones to the bioluminescent bacterium Vibrio fischeri.},
  author={Backhaus and Scholze and Grimme},
  journal={Aquatic toxicology},
  year={2000},
  volume={49 1-2},
  pages={49-61}
}
Quinolones are one of the most important group of synthetic antibiotics used in aquaculture. We studied the single substance and mixture toxicity of ten quinolones using a long term bioluminescence inhibition assay with the marine bacterium Vibrio fischeri as the test organism. All tested quinolones are highly toxic to the test organism with EC50 values ranging from 14 µg/l for ofloxacin to 1020 µg/l for pipemidic acid. Adapting the approach outlined in EEC directive 93/21/EEC to these results… CONTINUE READING
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