The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae.

@article{Val2005TheSG,
  title={The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae.},
  author={Maria Val and Marie Bouvier and Javier Guillen Campos and David Sherratt and Francois H. Cornet and Didier Mazel and François-Xavier Barre},
  journal={Molecular cell},
  year={2005},
  volume={19 4},
  pages={
          559-66
        }
}
A major determinant of Vibrio cholerae pathogenicity, the cholera enterotoxin, is encoded in the genome of an integrated phage, CTXvarphi. CTXvarphi integration depends on two host-encoded tyrosine recombinases, XerC and XerD. It occurs at dif1, a 28 bp site on V. cholerae chromosome 1 normally used by XerCD for chromosome dimer resolution. The replicative form of the phage contains two pairs of binding sites for XerC and XerD in inverted orientations. Here we show that in the single-stranded… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

A new family of mobiizable suicide plasmids based on the broad host range R388 plasid (IncW) or RP4 plasmid (IncPa) conjugative machineries and heir cognate E.coli host strains

  • G. emarre, A. M. Guerout, C. Matsumoto-Mashimo, D. A. Rowe-Magus, P. Marlière, D. Mazel
  • Res. Microbiol.,
  • 2005

lFtsK activities in Xer recombination , DNA mobilization and cell diviYsion involve overlapping and separate domains of the protein

  • S. cBigot, J. Corre, J. Louarn, F. Cornet, F. X. Barre
  • Mol . sMicrobiol .
  • 2004

ntegron integrase binds to bulged hairpin DNA

  • C. ohansson, M. Kamali-Moghaddam, L. Sundstrom
  • Nucleic Acids Res
  • 2004

symmetric activation of Xer site-specific recombination by FtsK

  • T. H. assey, L. Aussel, Barre, F.-X, D. J. Sherratt
  • MBO Rep
  • 2004

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