The single-pass cerebral extraction and capillary permeability-surface area product of several putative cerebral blood flow imaging agents.

Abstract

We have determined cerebral blood flow (CBF) and the single-pass cerebral extraction (E) of several putative agents for external imaging of CBF. Simultaneous measurements of blood flow and extraction were performed in 106 rats. For all agents, comparison of linear and exponential regressions of E on CBF indicates that this relationship can be described as… (More)

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@article{Rocco1993TheSC, title={The single-pass cerebral extraction and capillary permeability-surface area product of several putative cerebral blood flow imaging agents.}, author={Roberta Di Rocco and Diana Silva and Bozena Kuczynski and Rupa Narra and K. Ramalingam and Silvia S Jurisson and Adrian D. Nunn and W. C. Eckelman}, journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine}, year={1993}, volume={34 4}, pages={641-8} }