The single nucleotide polymorphism CRTh2 rs533116 is associated with allergic asthma and increased expression of CRTh2

  title={The single nucleotide polymorphism CRTh2 rs533116 is associated with allergic asthma and increased expression of CRTh2},
  author={E. Campos Alberto and E. Maclean and C. Davidson and N. Palikhe and J. Storie and C. Tse and D. Brenner and I. Mayers and H. Vliagoftis and A. El-Sohemy and L. Cameron},
  • E. Campos Alberto, E. Maclean, +8 authors L. Cameron
  • Published 2012
  • Biology, Medicine
  • Allergy
  • CRTh2 (chemoattractant‐receptor homologous molecule expressed on Th2 cells) is expressed by Th2 cells and other cells involved in allergic inflammation. Single nucleotide polymorphisms (SNPs) in CRTh2 (rs11571288, rs545659, rs634681) have been associated with various phenotypes of allergy in ethnically distinct populations. Here, we assessed the association between CRTh2 rs533116 and allergic asthma, expression of CRTh2 and Th2 cytokine production. 
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