The single-nucleotide addition cycle in transcription: a biophysical and biochemical perspective.

@article{Erie1992TheSA,
  title={The single-nucleotide addition cycle in transcription: a biophysical and biochemical perspective.},
  author={Dorothy Erie and Thomas Yager and Peter H. von Hippel},
  journal={Annual review of biophysics and biomolecular structure},
  year={1992},
  volume={21},
  pages={379-415}
}
This review has summarized the known features of the single-nucleotide addition reaction cycle in transcription. The reader will have noted that the information available is very incomplete, and that, in some cases, related experiments seem to lead to contradictory conclusions. We have tried to point out these discrepancies as they occur and to indicate areas where more experimentation is needed. We look forward to the day when all the microscopic steps of the single-nucleotide addition cycle… CONTINUE READING