The simultaneous quantification of dopamine, norepinephrine and epinephrine in micropunched rat brain nuclei by on-line trace enrichment HPLC with electrochemical detection: Distribution of catecholamines in the limbic system.

@article{Kilts1986TheSQ,
  title={The simultaneous quantification of dopamine, norepinephrine and epinephrine in micropunched rat brain nuclei by on-line trace enrichment HPLC with electrochemical detection: Distribution of catecholamines in the limbic system.},
  author={Clinton D. Kilts and Christopher M Anderson},
  journal={Neurochemistry international},
  year={1986},
  volume={9 3},
  pages={437-45}
}
A method is described for the simultaneous quantification of dopamine, norepinephrine and epinephrine in microdissected rat brain nuclei using on-line trace enrichment high performance liquid chromatography (HPLC) and electrochemical detection (EC). The method is specific, sensitive and rapid with lower limits of detection comparable to those of radioenzymatic and mass fragmentographic techniques. The ideal application of the method to determinations in discrete microdissected brain nuclei is… CONTINUE READING