The similarity index and DNA fingerprinting.

  title={The similarity index and DNA fingerprinting.},
  author={Michael Lynch},
  journal={Molecular biology and evolution},
  volume={7 5},
DNA-fingerprint similarity is being used increasingly to make inferences about levels of genetic variation within and between natural populations. It is shown that the similarity index--the average fraction of shared restriction fragments--provides upwardly biased estimates of population homozygosity but nearly unbiased estimates of the average identity-in-state for random pairs of individuals. A method is suggested for partitioning the DNA-fingerprint dissimilarity into within- and between… CONTINUE READING
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‘ A note on Nei ’ s measure of gene diversity in a substructured population

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Maximum likelihood estimation of the number of nucleotide substitutions from restriction sites data

  • Genetics

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