The significance of the nuclear and cytoplasmic localization of metallothionein in human liver and tumor cells.

@article{Cherian1994TheSO,
  title={The significance of the nuclear and cytoplasmic localization of metallothionein in human liver and tumor cells.},
  author={M. George Cherian},
  journal={Environmental Health Perspectives},
  year={1994},
  volume={102},
  pages={131 - 135}
}
Metallothioneins are a group of low-molecular-weight intracellular proteins present in high levels in fetal mammalian livers, bound to zinc and copper. They are also present in two major isoforms in low basal levels in various organs of adults in several species. Although a number of functions have been proposed for metallothioneins, their major biological roles may be in the storage of zinc and copper during rapid growth and development, and also in the detoxification of certain toxic metals… CONTINUE READING

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