The significance of molecular studies in the long-term follow-up of children with beckwith- wiedemann syndrome.

@article{Giewska2014TheSO,
  title={The significance of molecular studies in the long-term follow-up of children with beckwith- wiedemann syndrome.},
  author={Maria Giżewska and Malgorzata Wilk and Michal Patalan and Deborah M Mackay and Jaroslow Peregud-Pegorzelski and Elżbieta Gawrych and Mieczyslaw Walczak and Elzibieta Petriczko and Andrzej Brodkiewicz},
  journal={The Turkish journal of pediatrics},
  year={2014},
  volume={56 2},
  pages={177-82}
}
Beckwith-Wiedemann syndrome (BWS) is a congenital disorder of imprinting caused by epimutations and mutations affecting two imprinted loci on chromosome 11p15. Its clinical features are heterogeneous, including macrosomia, macroglossia, hemihyperplasia, abdominal wall defects, neonatal hypoglycemia, and increased risk of embryonal tumors such as Wilms tumor… CONTINUE READING