The significance of aberrant crypt foci in understanding the pathogenesis of colon cancer.

@article{Bird2000TheSO,
  title={The significance of aberrant crypt foci in understanding the pathogenesis of colon cancer.},
  author={Ranjana P. Bird and Carolyn K Good},
  journal={Toxicology letters},
  year={2000},
  volume={112-113},
  pages={395-402}
}
Animal models provide a unique opportunity to study the biology of the disease process, and to test hypotheses linking environmental factors in the etiology and prevention of colon cancer. The concept of cancer prevention is to retard, regress or eliminate precancerous lesions. To actuate this concept, it is important to identify and enumerate preneoplastic lesions of various growth dimensions. The study of the precancerous stages in the colon is possible by the identification of aberrant crypt… CONTINUE READING
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