The significance of Toll-like receptor 4 (TLR4) expression in patients with chronic hepatitis B.

@article{Wei2008TheSO,
  title={The significance of Toll-like receptor 4 (TLR4) expression in patients with chronic hepatitis B.},
  author={Xiu-qing Wei and Yun-wei Guo and Jia-jun Liu and Zhuo-fu Wen and Shao-ji Yang and Ji-lu Yao},
  journal={Clinical and investigative medicine. Medecine clinique et experimentale},
  year={2008},
  volume={31 3},
  pages={E123-30}
}
PURPOSE To investigate the importance of Toll-like receptor 4 (TLR4) expression on hepatocytes obtained from Chronic Hepatitis B patients as well as on hepatocellular carcinoma HepG2 and HepG2.2.15 cell lines. METHODS Expression of TLR4 in liver tissues was determined by immunohistochemistry in 75 patients with CHB and in10 healthy controls. The protein and mRNA 1eve1s of TLR4 in hepatocellular carcinoma HepG2 and HepG2.2.15 cells were measured by flow cytometry (FCM) and real-time… CONTINUE READING