The significance of E266K polymorphism in the NOD1 gene on Helicobacter Pylori infection: an effective force on pathogenesis?

@article{Kara2009TheSO,
  title={The significance of E266K polymorphism in the NOD1 gene on Helicobacter Pylori infection: an effective force on pathogenesis?},
  author={Banu Kivanc Kara and Hikmet Akkiz and Figen Doran and Suleyman Nuri Bayram and Eren Erken and Yuksel Gumurdullu and Macit U. Sandikci},
  journal={Clinical and Experimental Medicine},
  year={2009},
  volume={10},
  pages={107-112}
}
The severity of Helicobacter pylori-related diseases varies greatly among infected individuals and seems to be influenced by both host and bacterial factors. Infection with a cytotoxin-associated gene pathogenicity island (Cag PAI)-positive H. Pylori strain causes a higher grade of gastric mucosal inflammation than an infection caused by a negative strain. Furthermore, such an infection is associated with severe atrophic gastritis and gastric adenocarcinoma. NOD1 protein is a cytosolic pattern… CONTINUE READING
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[Single nucleotide polymorphisms and helicobacter pylori-related gastric cancer].

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