The signature of selection mediated by expression on human genes.

Abstract

As the efficacy of natural selection is expected to be a function of population size, in humans it is usually presumed that selection is a weak force and hence that gene characteristics are mostly determined by stochastic forces. In contrast, in species with large population sizes, selection is expected to be a much more effective force. Evidence for this… (More)

Topics

Cite this paper

@article{Urrutia2003TheSO, title={The signature of selection mediated by expression on human genes.}, author={Araxi O Urrutia and Laurence D Hurst}, journal={Genome research}, year={2003}, volume={13 10}, pages={2260-4} }