The signaling pathway of rhodopsin.

@article{Kong2007TheSP,
  title={The signaling pathway of rhodopsin.},
  author={Yifei Kong and Martin Karplus},
  journal={Structure},
  year={2007},
  volume={15 5},
  pages={611-23}
}
The signal-transduction mechanism of rhodopsin was studied by molecular dynamics (MD) simulations of the high-resolution, inactive structure in an explicit membrane environment. The simulations were employed to calculate equal-time correlations of the fluctuating interaction energy of residue pairs. The resulting interaction-correlation matrix was used to determine a network that couples retinal to the cytoplasmic interface, where transducin binds. Two highly conserved motifs, D(E)RY and NPxxY… CONTINUE READING

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