The signaling mechanism of ROS in tumor progression

@article{Wu2006TheSM,
  title={The signaling mechanism of ROS in tumor progression},
  author={W S Wu},
  journal={Cancer and Metastasis Reviews},
  year={2006},
  volume={25},
  pages={695-705}
}
Reactive oxygen species (ROS) are recently proposed to be involved in tumor metastasis which is a complicated processes including epithelial–mesenchymal transition (EMT), migration, invasion of the tumor cells and angiogenesis around the tumor lesion. ROS generation may be induced intracellularly, in either NADPH oxidase- or mitochondria-dependent manner, by growth factors and cytokines (such as TGFβ and HGF) and tumor promoters (such as TPA) capable of triggering cell adhesion, EMT and… CONTINUE READING
Highly Influential
This paper has highly influenced 16 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS