The siderophore iron transporter of Candida albicans (Sit1p/Arn1p) mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion.

Abstract

The human fungal pathogen Candida albicans contains a close homologue of yeast siderophore transporters, designated Sit1p/Arn1p. We have characterized the function of SIT1 in C. albicans by constructing sit1 deletion strains and testing their virulence and ability to utilize a range of siderophores and other iron complexes. sit1 mutant strains are defective… (More)

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@article{Heymann2002TheSI, title={The siderophore iron transporter of Candida albicans (Sit1p/Arn1p) mediates uptake of ferrichrome-type siderophores and is required for epithelial invasion.}, author={Petra Heymann and Michaela Gerads and Martin Alexander Schaller and Françoise Dromer and G{\"{u}nther Winkelmann and J. F. Ernst}, journal={Infection and immunity}, year={2002}, volume={70 9}, pages={5246-55} }