The shortcomings of clinical trials assessing the efficacy of probiotics in irritable bowel syndrome.

BACKGROUND Multiple clinical trials within the past decade have aimed to study the safety and efficacy of various probiotic strains in treating patients with irritable bowel syndrome (IBS). However, there exists much heterogenicity in study design among these trials, namely, in bacterial strain, dose, dosage form, sample size, study duration, and population… CONTINUE READING