The sheathed flagellum of Brucella melitensis is involved in persistence in a murine model of infection.

@article{Fretin2005TheSF,
  title={The sheathed flagellum of Brucella melitensis is involved in persistence in a murine model of infection.},
  author={David Fretin and Alan Fauconnier and Stephan Koehler and Shirley M. Halling and Sandrine L{\'e}onard and Caroline Nijskens and Jonathan Ferooz and Pascal Lestrate and R-M Delrue and Isabelle Danese and Jean Vandenhaute and Anne Tibor and X DeBolle and J J Letesson},
  journal={Cellular microbiology},
  year={2005},
  volume={7 5},
  pages={687-98}
}
Persistence infection is the keystone of the ruminant and human diseases called brucellosis and Malta fever, respectively, and is linked to the intracellular tropism of Brucella spp. While described as non-motile, Brucella spp. have all the genes except the chemotactic system, necessary to assemble a functional flagellum. We undertook to determine whether these genes are expressed and are playing a role in some step of the disease process. We demonstrated that in the early log phase of a growth… CONTINUE READING

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