The shape of the dose-response curve for radiation-induced neoplastic transformation in vitro: evidence for an adaptive response against neoplastic transformation at low doses of low-LET radiation.

@article{Redpath2001TheSO,
  title={The shape of the dose-response curve for radiation-induced neoplastic transformation in vitro: evidence for an adaptive response against neoplastic transformation at low doses of low-LET radiation.},
  author={J. Leslie Redpath and D Liang and Thomas H. Taylor and Charlene Christie and Eugene Elmore},
  journal={Radiation research},
  year={2001},
  volume={156 6},
  pages={700-7}
}
A dose-response curve for gamma-radiation-induced neoplastic transformation of HeLa x skin fibroblast human hybrid cells over the dose range 0.1 cGy to 1 Gy is presented. In the experimental protocol used, the spontaneous (background) frequency of neoplastic transformation of sham-irradiated cultures was compared to that of cultures which had been irradiated with (137)Cs gamma radiation and either plated immediately or held for 24 h at 37 degrees C prior to plating, for assay for neoplastic… CONTINUE READING
Highly Influential
This paper has highly influenced 18 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 65 extracted citations

Protective bystander effects simulated with the state-vector model.

Dose-response : a publication of International Hormesis Society • 2007
View 19 Excerpts
Highly Influenced

Radiation hormesis: historical perspective and implications for low-dose cancer risk assessment.

Dose-response : a publication of International Hormesis Society • 2010
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…