The sex difference in type II cell surfactant synthesis originates in the fibroblast in vitro.

@article{Torday1984TheSD,
  title={The sex difference in type II cell surfactant synthesis originates in the fibroblast in vitro.},
  author={John Steven Torday},
  journal={Experimental lung research},
  year={1984},
  volume={7 3-4},
  pages={187-94}
}
Lung from 19 days' gestation male and female rat fetuses was grown in mixed monolayer culture. Cultures from female lungs synthesized twice as much 3H-saturated phosphatidylcholine (3H-SPC) from 3H-choline as cultures from male lungs. Preincubation with cortisol caused a doubling in 3H-SPC synthesis by cultures from both sexes. Study of sex-specific… CONTINUE READING