The sevenless+ protein is expressed apically in cell membranes of developing Drosophila retina; it is not restricted to cell R7.


In the sevenless (sev) mutants of Drosophila, a single cell type, photoreceptor R7, does not develop. We made monoclonal antibody against a sev+-beta-galactosidase fusion protein, and used it to determine the ultrastructural localization of the sev+ protein in the larval eye disc. The protein is expressed on the apical surface of the developing retina. It… (More)


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