The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF)

@article{Hamann1996TheST,
  title={The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF)},
  author={Joerg Hamann and Bjoern Vogel and Gijs M W van Schijndel and Ren{\'e} A W van Lier},
  journal={The Journal of Experimental Medicine},
  year={1996},
  volume={184},
  pages={1185 - 1189}
}
CD97 is an activation-induced antigen on leukocytes with a seven-span transmembrane (7-TM) region homologous to the secretin receptor superfamily. However, in contrast to this group of peptide hormone receptors, CD97 has an extended extracellular region with three EGF domains at the NH2 terminus, two of them with a calcium binding site. By demonstrating that lymphocytes and erythrocytes specifically adhere to CD97-transfected COS cells we here show that CD97 in parallel with its molecular… CONTINUE READING

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