The serotonin transporter gene polymorphism is not associated with smoking behavior

@article{Trummer2006TheST,
  title={The serotonin transporter gene polymorphism is not associated with smoking behavior},
  author={Olivia Trummer and Herwig K{\"o}ppel and ThomasC. Wascher and Gerda Gruenbacher and Manuela Gutjahr and Olaf H. Stanger and Sigrid Ramschak-Schwarzer and B O Boehm and Bernhard Rudolf Winkelmann and Winfried Maerz and Wilfried Renner},
  journal={The Pharmacogenomics Journal},
  year={2006},
  volume={6},
  pages={397-400}
}
Nicotine increases serotonin release in the brain and symptoms of nicotine withdrawal may be modulated by diminished serotonergic neurotransmission. The promoter region of the serotonin transporter gene, solute carrier family neurotransmitter transporter member 4 (SLC6A4), contains a functional tandem repeat polymorphism. The long (L) variant is more actively transcribed than the short (S) variant and is associated with a higher serotonin uptake. To investigate the potential role of this… CONTINUE READING
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