The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cortisol stress reactivity: a meta-analysis

@article{Miller2013TheST,
  title={The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cortisol stress reactivity: a meta-analysis},
  author={Ryan Miller and Matthis Wankerl and Tobias Stalder and Clemens Kirschbaum and Nina Alexander},
  journal={Molecular Psychiatry},
  year={2013},
  volume={18},
  pages={1018-1024}
}
Recent meta-analyses have stimulated an active debate on whether the serotonin transporter gene-linked polymorphic region (5-HTTLPR) is associated with an elevated vulnerability to psychiatric diseases upon exposure to environmental adversity. As a potential mechanism explaining genotype-dependent differences in stress sensitivity, altered stress-induced activation of the hypothalamus-pituitary-adrenal (HPA) axis has been investigated in several experimental studies, with most of these studies… CONTINUE READING

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