The serotonergic modulation of synaptic plasticity in the rat hippocampo-medial prefrontal cortex pathway.

@article{Ohashi2003TheSM,
  title={The serotonergic modulation of synaptic plasticity in the rat hippocampo-medial prefrontal cortex pathway.},
  author={Satoshi Ohashi and Machiko Matsumoto and Hiroko Togashi and Ken-ichi Ueno and Mitsuhiro Yoshioka},
  journal={Neuroscience letters},
  year={2003},
  volume={342 3},
  pages={179-82}
}
The ability of the serotonergic (5-HTergic) system to affect the hippocampo-medial prefrontal cortex (mPFC) synaptic properties was examined in rats with lesions of 5-HTergic neurons. Intracerebroventricular injections of 5,7-dihydroxytryptamine (5,7-DHT) resulted in selective depletion of 5-HT and 5-hydroxyindoleacetic acid in the cerebral cortex… CONTINUE READING