The sequential analysis of trisomy 12 in B-cell chronic lymphocytic leukaemia.

Abstract

In this longitudinal study we evaluated the clinical significance of screening for trisomy 12 by fluorescence in situ hybridization (FISH) and correlated these findings with survival, disease progression and need for treatment. Interphase FISH was performed on 85 patients in 1993/94 and repeated on 41 patients in 1996/97. Over the 4-year period there was no… (More)

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@article{Auer1999TheSA, title={The sequential analysis of trisomy 12 in B-cell chronic lymphocytic leukaemia.}, author={R L Auer and Nicola Bienz and J. M. M. Neilson and M. Cai and John Waters and Don W. Milligan and Christopher Fegan}, journal={British journal of haematology}, year={1999}, volume={104 4}, pages={742-4} }