The sequence of phenylalanine tRNA from E. coli

  title={The sequence of phenylalanine tRNA from E. coli},
  author={Bart Barrell and Frederick Sanger},
  journal={FEBS Letters},
Physiological and biochemical studies on the function of 5-methyluridine in the transfer ribonucleic acid of Escherichia coli
This experiment provides the first indication of the overall value of m5U in tRNA, which seemed to have a distinct advantage over cells lacking this modified nucleoside in a mixed population experiment.
Transfer ribonucleic acid from Mycoplasma laidlawii A.
Cross-reactions in heterologous systems from M. laidlawii A, Escherichia coli, and yeast were studied in some detail and Aminoacylation was possible in all combinations of methionine specific tRNAs and enzymes.
The use of rifampicin to evaluate tRNA transcriptional organization in Escherichia coli.
The antibiotic rifampicin was used to explore tRNA gene transcriptional organization in Escherichia coli and the protocols developed should be applicable to most prokaryotes.
Comparison of Escherichia coli tRNAPhe in the free state, in the ternary complex and in the ribosomal A and P sites by chemical probing.
The results correlate well with the three-dimensional structure of tRNAPheyeast determined by X-ray studies, and the pattern of reactivity was not affected either by charging the tRNA with phenylalanine or by labelling the 3' terminus with pCp.


Primary Structure of a Methionine Transfer RNA from Escherichia coli
The complete nucleotide sequence of tRNAM is reported, which appears to be the polypeptide chain initiating tRNA in bacterial systems and places methionine into internal positions of growingpolypeptides.
RNA Codewords and Protein Synthesis
Property of the codeword recognition process and the minimum oligonucleotide chain length required to induce such interactions are presented, and the modification of RNA and DNA codewords, converting sense into missense or nonsense codewording, is suggested as a possible regulatory mechanism in protein synthesis.