The sensitizing capacity of ginkgolic acids in guinea pigs.

  title={The sensitizing capacity of ginkgolic acids in guinea pigs.},
  author={Bjoern M Hausen},
  journal={American journal of contact dermatitis : official journal of the American Contact Dermatitis Society},
  volume={9 3},
  • Bjoern M Hausen
  • Published 1998 in
    American journal of contact dermatitis : official…
BACKGROUND Ginkgo biloba possesses fruits that have caused numerous cases of allergic contact dermatitis. Low amounts of the ginkgolic acids occur in the leaves as well. OBJECTIVE Leaf extracts are used to treat cerebrovascular and peripheral vascular disorders. The question arises whether skin hypersensitivity reactions may be adverse effects because the pharmaceutical preparations contain low amounts of ginkgolic acids. METHODS Guinea pigs were sensitized experimentally with pure… CONTINUE READING