The sensitization of high threshold mechanoreceptors with myelinated axons by repeated heating.

@article{Fitzgerald1977TheSO,
  title={The sensitization of high threshold mechanoreceptors with myelinated axons by repeated heating.},
  author={Maria Fitzgerald and Bruce Lynn},
  journal={The Journal of physiology},
  year={1977},
  volume={265 2},
  pages={549-63}
}
1. Seventy high threshold mechanoreceptor units (HTMs) with myelinated axons were isolated from the sural nerves of cats and rabbits. Thirteen cat and forty-two rabbit HTMs were testec by controlled, repeated heating of the skin of the foot or lower leg to noxious levels. 2. Many of the units (77% in the cat and 40% in the rabbit) fired to heating. Only six (11%) of these fired to the first brief heating to 50-55 degrees C. The rest required 2-6 heat trials before responding. 3. Heat responding… CONTINUE READING