The sensitivity to hyperbaric oxygen of human diploid fibroblasts during ageing in vitro.


The effect of hyperbaric oxygen on human diploid fibroblasts, WI-38, at various passages was examined. Their colony-forming ability deteriorates on exposure to hyperbaric oxygen. The cellular injury is not due to the high pressure per se, but to oxygen toxicity, since compressed nitrogen has no effect on the cells. When the cells beyond mid-40 population… (More)


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