The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum.

@article{Bosse2008TheSD,
  title={The selective delta opioid agonist SNC80 enhances amphetamine-mediated efflux of dopamine from rat striatum.},
  author={Kelly E. Bosse and Emily M Jutkiewicz and Margaret E. Gnegy and John R. Traynor},
  journal={Neuropharmacology},
  year={2008},
  volume={55 5},
  pages={755-62}
}
The highly selective delta opioid agonist, SNC80, elicits dopamine-related behaviors including locomotor stimulation and conditioned place-preference. In contrast, it has been reported that SNC80 fails to promote dopamine efflux from the striatum of freely moving rats. However, SNC80 does enhance behavioral responses to the stimulants, amphetamine and cocaine, suggesting an interaction between delta opioids and psychostimulants. Since the increase in locomotor activity elicited by amphetamine… CONTINUE READING