The selective breakdown of frontal functions in patients with obsessive–compulsive disorder and in patients with schizophrenia: A double dissociation experimental finding

@article{Abbruzzese1997TheSB,
  title={The selective breakdown of frontal functions in patients with obsessive–compulsive disorder and in patients with schizophrenia: A double dissociation experimental finding},
  author={Massimo Abbruzzese and Stefano Ferri and Silvio Scarone},
  journal={Neuropsychologia},
  year={1997},
  volume={35},
  pages={907-912}
}
In an our recent preliminary study, we reported the neuropsychological finding of a double dissociation in the frontal lobe functioning between 25 OCD patients and 25 schizophrenics. The first group performed normally in the Wisconsin Card Sorting Test (WCST), which is considered sensitive to Dorso-Lateral Prefrontal Cortex (DLPFC) dysfunctions and abnormally to the Object Alternation Test (OAT), which has been proposed as a tool sensitive to Orbito-Frontal Cortex (OFC); on the other hand… CONTINUE READING

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