The selective RNA-binding protein quaking I (QKI) is necessary and sufficient for promoting oligodendroglia differentiation.

@article{Chen2007TheSR,
  title={The selective RNA-binding protein quaking I (QKI) is necessary and sufficient for promoting oligodendroglia differentiation.},
  author={Yuntao Chen and Donghua Tian and L M Ku and Donna J. Osterhout and Yue Feng},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 32},
  pages={23553-60}
}
Quaking I (QKI) is a selective RNA-binding protein essential for myelination of the central nervous system. Three QKI isoforms with distinct C termini and subcellular localization, namely QKI-5, QKI-6, and QKI-7, are expressed in oligodendroglia progenitor cells (OPCs) prior to the initiation of myelin formation and implicated in promoting oligodendrocyte lineage development. However, the functional requirement for each QKI isoform and the mechanisms by which QKI isoforms govern OPC development… CONTINUE READING

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