The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH.

@article{Jensen2020TheS5,
  title={The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH.},
  author={Anders A. Jensen and Adam L. Halberstadt and Emil M{\"a}rcher-R{\o}rsted and Anna U Odland and Muhammad Rafique Chatha and Nikolaj Raahauge Speth and Gudrun Liebscher and Martin Hansen and Hans Br{\"a}uner‐Osborne and Mikael Palner and Jesper T. Andreasen and Jesper L. Kristensen},
  journal={Biochemical pharmacology},
  year={2020},
  pages={
          113979
        }
}
25CN‐NBOH: A Selective Agonist for in vitro and in vivo Investigations of the Serotonin 2A Receptor
TLDR
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TLDR
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Improving cognitive functioning in major depressive disorder with psychedelics: A dimensional approach

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TLDR
25CN-NBOH appears to be a superior selective and brain-penetrant 5-HT2A receptor agonist compared with (±)-2,5-dimethoxy-4-iodoamphetamine (DOI), and it is proposed that the compound could be a valuable tool for future investigations of physiologic functions mediated by this receptor.
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