The selection and application of ssDNA aptamers against MPT64 protein in Mycobacterium tuberculosis.

@article{Qin2009TheSA,
  title={The selection and application of ssDNA aptamers against MPT64 protein in Mycobacterium tuberculosis.},
  author={Lianhua Qin and Ruijuan Zheng and Zhanzhong Ma and Yonghong Feng and Zhonghua Liu and Hua Guang Yang and Jie Wang and Ruiliang Jin and Junmei Lu and Yuansheng Ding and Zhongyi Hu},
  journal={Clinical chemistry and laboratory medicine},
  year={2009},
  volume={47 4},
  pages={405-11}
}
BACKGROUND Tuberculosis (TB) remains a major health problem affecting millions of people worldwide. One-third of the world's population is infected with Mycobacterium tuberculosis, the etiologic agent of TB. A simple and rapid method to diagnose TB is urgently needed to be developed. The procedure of systematic evolution of ligands by exponential enrichment (SELEX) is a method in which single-stranded oligonucleotides (called aptamers) are selected from a wide variety of sequences, based on… CONTINUE READING
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