The secretory omega-class glutathione transferase OvGST3 from the human pathogenic parasite Onchocerca volvulus.

@article{Liebau2008TheSO,
  title={The secretory omega-class glutathione transferase OvGST3 from the human pathogenic parasite Onchocerca volvulus.},
  author={Eva Liebau and Jana H{\"o}ppner and Mareike M{\"u}hlmeister and Cora Burmeister and Kai L{\"u}ersen and Markus Perbandt and Christel Schmetz and Dietrich B{\"u}ttner and Norbert W Brattig},
  journal={The FEBS journal},
  year={2008},
  volume={275 13},
  pages={3438-53}
}
Onchocerciasis or river blindness, caused by the filarial nematode Onchocerca volvulus, is the second leading cause of blindness due to infectious diseases. The protective role of the omega-class glutathione transferase 3 from O. volvulus (OvGST3) against intracellular and environmental reactive oxygen species has been described previously. In the present study, we continue our investigation of the highly stress-responsive OvGST3. Alternative splicing of two exons and one intron retention… CONTINUE READING
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