The secretory mechanism in adrenal chromaffin cells by nitrophenol compounds: possible involvement of the change in the surface potentials.

@article{Yamagami1987TheSM,
  title={The secretory mechanism in adrenal chromaffin cells by nitrophenol compounds: possible involvement of the change in the surface potentials.},
  author={K. Yamagami and M. Sorimachi},
  journal={The Japanese journal of physiology},
  year={1987},
  volume={37 4},
  pages={
          643-56
        }
}
  • K. Yamagami, M. Sorimachi
  • Published 1987
  • Chemistry, Medicine
  • The Japanese journal of physiology
  • The rabbit adrenal gland was perfused with a modified Locke's medium and the mechanism of adrenaline secretion induced by nitrophenol compound was investigated. The secretory response to 2,4-dinitrophenol (DNP) or trinitrophenol (TNP) showed the following peculiar features. (1) Prolonged exposure to DNP or TNP caused an immediate, and long-lasting increase of secretion only in the presence of Ca. (2) The response to DNP depended on the concentration of Ca, but that to TNP was largest in the… CONTINUE READING

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