The secretion of amino acid transmitters from cerebellar primary cultures probed by alpha-latrotoxin.

Abstract

Using amino acid transmitter release, inositol phosphate production and 45Ca2+ accumulation as cellular responses to alpha-latrotoxin treatment, we studied the susceptibility of rat primary cerebellar granule cultures to toxin. Binding studies as well as immunofluorescence of toxin-treated cells, allow an evaluation of the expression, properties and… (More)

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