The secret life of histones

  title={The secret life of histones},
  author={Johannes Rudolph and Karolin Luger},
  pages={33 - 33}
Histone H3 leads a double life as a copper reductase Histone proteins are the ubiquitous organizers of all eukaryotic genomes (1). Two each of the histones H2A, H2B, H3, and H4 form a disk-shaped assembly around which 147 base pairs (bp) of DNA are tightly coiled. Hundreds of thousands of these connected nucleosomes wrap up further to form chromosomes. The substantial sequence conservation between eukaryotic histones and the presence of simple histones in archaea (the presumed ancestors of all… Expand
2 Citations
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