The second wave in kinase cancer drugs

@article{Garber2006TheSW,
  title={The second wave in kinase cancer drugs},
  author={Ken Garber},
  journal={Nature Biotechnology},
  year={2006},
  volume={24},
  pages={127-130}
}
When the US Food and Drug Association (FDA) gave its blessing in December to Nexavar (sorafenib), from Onyx Pharmaceuticals in Emeryville, California, it marked the fifth drug approval of a protein kinase inhibitor in the last four years for treating cancer. And the pace is quickening. Two more companies are awaiting almost certain FDA approval for their kinase inhibitors (Table 1) and at least 40 are in clinical trials, making kinases the second most popular drug target class in the… CONTINUE READING

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