The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function

@inproceedings{Cattaruzzi2007TheSA,
  title={The second AT-hook of the architectural transcription factor HMGA2 is determinant for nuclear localization and function},
  author={Giacomo Cattaruzzi and Sandro Altamura and Michela A. Tessari and Alessandra Rustighi and Vincenzo Giancotti and Carlo Pucillo and Guidalberto Manfioletti},
  booktitle={Nucleic acids research},
  year={2007}
}
  • Giacomo Cattaruzzi, Sandro Altamura, +4 authors Guidalberto Manfioletti
  • Published in Nucleic acids research 2007
  • Biology, Medicine
  • High Mobility Group A (HMGA) is a family of architectural nuclear factors which play an important role in neoplastic transformation. HMGA proteins are multifunctional factors that associate both with DNA and nuclear proteins that have been involved in several nuclear processes including transcription. HMGA localization is exclusively nuclear but, to date, the mechanism of nuclear import for these proteins remains unknown. Here, we report the identification and characterization of a nuclear… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 18 CITATIONS

    High Mobility Group A2 protects cancer cells against telomere dysfunction

    VIEW 4 EXCERPTS
    CITES BACKGROUND & METHODS
    HIGHLY INFLUENCED

    High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism

    VIEW 1 EXCERPT
    CITES BACKGROUND

    HMGA2 sustains self-renewal and invasiveness of glioma-initiating cells

    VIEW 1 EXCERPT
    CITES BACKGROUND

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 34 REFERENCES

    Retinoid-dependent recruitment of a histone H1 displacement activity by retinoic acid receptor.

    VIEW 4 EXCERPTS
    HIGHLY INFLUENTIAL

    A novel role for high-mobility group a proteins in cellular senescence and heterochromatin

    • M. Narita, V. Krizhanovsky, +4 authors S. W. Lowe
    • formation. Cell,
    • 2006
    VIEW 1 EXCERPT