The seco-iridoid pathway from Catharanthus roseus

@article{Miettinen2014TheSP,
  title={The seco-iridoid pathway from Catharanthus roseus},
  author={Karel Miettinen and Lemeng Dong and Nicolas Navrot and T. Schneider and V. Burlat and Jacob Pollier and L. Woittiez and Sander van der Krol and Rapha{\"e}l Lugan and Tina Ilc and R. Verpoorte and K. Oksman-Caldentey and E. Martinoia and H. Bouwmeester and A. Goossens and J. Memelink and D. Werck-Reichhart},
  journal={Nature Communications},
  year={2014},
  volume={5}
}
  • Karel Miettinen, Lemeng Dong, +14 authors D. Werck-Reichhart
  • Published 2014
  • Biology, Medicine
  • Nature Communications
    • The (seco)iridoids and their derivatives, the monoterpenoid indole alkaloids (MIAs), form two large families of plant-derived bioactive compounds with a wide spectrum of high-value pharmacological and insect-repellent activities. Vinblastine and vincristine, MIAs used as anticancer drugs, are produced by Catharanthus roseus in extremely low levels, leading to high market prices and poor availability. Their biotechnological production is hampered by the fragmentary knowledge of their… CONTINUE READING
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    266 Citations
    Highly Influential Citations
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    Background Citations
    99
    Methods Citations
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    Results Citations
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    266 Citations
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    Citation Type

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    Inter-organ transport of secologanin allows assembly of monoterpenoid indole alkaloids in a Catharanthus roseus mutant.
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    Exploring the production of high-value compounds in plant Catharanthus roseus hairy roots and yeast Yarrowia lipolytica
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    Sem título-1
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    Biotechnological Interventions to Modulate Terpenoid Indole Alkaloid Pathway in Catharanthus roseus Using In Vitro Tools and Approaches

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