The search for unrecognized pathogens.

  title={The search for unrecognized pathogens.},
  author={David A. Relman},
  volume={284 5418},
The distribution and diversity of microorganisms in the world are far greater than have been previously appreciated. Molecular, cultivation-independent methods have played a key role in this insight. To what extent do humans remain ignorant of microbial diversity within the human body and the settings in which microorganisms cause human disease? In addition to implicating microbial agents in nontraditional infectious diseases, the use of methods such as broad-range polymerase chain reaction… CONTINUE READING

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