The search for circadian clock components in humans: new perspectives for association studies.

@article{Allebrandt2008TheSF,
  title={The search for circadian clock components in humans: new perspectives for association studies.},
  author={Karla Viviani Allebrandt and Till Roenneberg},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2008},
  volume={41 8},
  pages={716-21}
}
Individual circadian clocks entrain differently to environmental cycles (zeitgebers, e.g., light and darkness), earlier or later within the day, leading to different chronotypes. In human populations, the distribution of chronotypes forms a bell-shaped curve, with the extreme early and late types _ larks and owls, respectively _ at its ends. Human chronotype, which can be assessed by the timing of an individual's sleep-wake cycle, is partly influenced by genetic factors - known from animal… CONTINUE READING