The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II.

  title={The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II.},
  author={J. S. Zhu and Georges M. Halpern and K Jones},
  journal={Journal of alternative and complementary medicine},
  volume={4 4},
Cordyceps sinensis (Berk.) Sacc. is a time-honored tonic food and herbal medicine in China, where recent research has shown that many of its traditional uses may be viewed from the basis of pharmacological activities. The ongoing exploration of C. sinensis in its wild form and cultured, fermented mycelial products derived from it, are reviewed from English and Chinese literature. Part II concludes the series with a review of C. sinensis in preclinical in vitro and in vivo studies, and open… 

Pharmacological functions of Chinese medicinal fungus Cordyceps sinensis and related species

Adjuvant therapy using C. sinensis for immune function disturbances, cancer, and renal failure is possible if double-blind, randomized placebo-control clinical studies show the efficacy of this herb.

Pharmacology, phytochemistry and traditional uses of Cordyceps sinensis (Berk.) Sacc: A recent update for future prospectsa

This review highlights the pharmacology, biological properties and traditional uses of a very important folklore medicine, known as ‘Keeda jadi’. In nature, it is found at high altitudes of 3500-5000

Traditional uses and medicinal potential of Cordyceps sinensis of Sikkim

It was found that most local folk healers/traditional healers use cordyceps for the treatment of 21 ailments and more mechanism-based and disease-oriented clinical studies are recommended.

Quantification of Flavonoids and Nucleoside by UPLC-MS in Indian Cordyceps sinensis and its in- vitro Cultures

Results indicate that both the extracts of Cordyceps sinensis have almost similar concentration of the kaempferol, isorhamnetin and cordycepin which supports use of in vitro biomass as an alternative source of medicine.

Pharmacological and therapeutic potential of Cordyceps with special reference to Cordycepin

The article also reviews the current efforts to delineate the mechanism of action of Cordycepin in various bio-molecular processes and will certainly draw the attention of scientific community to improve the bioactivity and production of CordYcepin for its commercial use in pharmacological and medical fields.

Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease.

Cordyceps preparation, as an adjuvant therapy to conventional medicine, showed potential promise to decrease serum creatinine, increase creatine clearance, reduce proteinuria and alleviate CKD-associated complications, such as increased haemoglobin and serum albumin.



The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I.

This review presents Cordyceps sinensis (Berk.) Sacc., a fungus highly valued in China as a tonic food and herbal medicine. The extant records show the continued use of C. sinensis is now centuries

Polysaccharides in fungi. XXXII. Hypoglycemic activity and chemical properties of a polysaccharide from the cultural mycelium of Cordyceps sinensis.

A neutral polysaccharide (CS-F30) exhibited higher hypoglycemic activity than its crudePolysaccharides showed significant activity in normal mice and streptozotocin-induced diabetic mice as a result of intraperitoneal (i.p.) injection, and it significantly lowered the glucose level by p.p. administration.

Cordyceps sinensis as an immunomodulatory agent.

The results indicated that neither CS-36-39 nor CS-48-51 was cytotoxic on HMNC, and that immunosuppressive ingredients are contained in Cordyceps sinensis.

Polysaccharides in fungi. XXXVI. Hypoglycemic activity of a polysaccharide (CS-F30) from the cultural mycelium of Cordyceps sinensis and its effect on glucose metabolism in mouse liver.

A polysaccharide (CS-F30) obtained from the cultural mycelium of Cordyceps sinensis showed potent hypoglycemic activity in genetic diabetic mice after intraperitoneal administration, and the plasma

Effects of cordyceps sinensis on natural killer activity and colony formation of B16 melanoma.

It is indicated that CS-II may be used as an immunopotentiating agent in treating cancer and immunodeficient patients.

[Cordyceps sinensis in protection of the kidney from cyclosporine A nephrotoxicity].

Both acute and chronic experiments showed that CS could protect the kidney from CsA-Nx and ameliorate the glomerular and interstitial injuries.

Amelioration of cyclosporin nephrotoxicity by Cordyceps sinensis in kidney-transplanted recipients.

  • F. XuJ. B. HuangL. JiangJ. XuJ. Mi
  • Medicine
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 1995