• Corpus ID: 21643842

The science of cultivating happiness : role of ( endo ) cannabinoids

  title={The science of cultivating happiness : role of ( endo ) cannabinoids},
  author={Tanja Bagar and Jason M. B. Wilson},
The role of the endocannabinoid system (ECS) in human physiology is well documented and scientifically supported. There is a large body of evidence that the endocannabinoids regulate mood, emotion, motivation, memory, pleasure perception, appetite, metabolism and more. The connection between cannabinoids and emotional states has long been empirically and scientifically established. Even the first discovered active constituent of the hemp plant Cannabis sativa, delta9-tetrahydrocannabinol… 
1 Citations

Happiness ‟-The Role of Neurochemicals

It can be concluded that the major endogenous factors that exaggerate the feeling of happiness or bring about itself are the release and actions of such neurochemicals.



Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors

It is found that specific effects of THC such as memory deficits, anxiolytic-like effects, and social interaction are under the control of 5-HT2AR, but its acute hypolocomotor, hypothermic, anxiogenic, and antinociceptive effects are not.

Genetic Variations in the Human Cannabinoid Receptor Gene Are Associated with Happiness

The cytosine allele carriers of the human cannabinoid receptor 1 gene, who are sensitive to positive emotional stimuli, exhibited greater magnitude positive emotions when they experienced positive events and had a higher subjective happiness level than thymine-thymine carriers.

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

Serotonin Evokes Endocannabinoid Release and Retrogradely Suppresses Excitatory Synapses

The results indicate that serotonin activates 5-HT2Rs on IO neurons, thereby releasing endocannabinoids that act retrogradely to suppress glutamate release by activating presynaptic CB1Rs, establishing a link between serotonin signaling and endOCannabinoid signaling.

Treatment-resistant schizophrenia: What's next

and moderate alcohol consumption on endocannabinoids and N-acylethanolamines in humans: a randomized crossover trial

  • PLoS One. 2015 May 11;10(5):e0126421. Schultz, S
  • 2010