The science news that shaped 2021: Nature's picks.

  title={The science news that shaped 2021: Nature's picks.},
  • Published 14 December 2021
  • Medicine
  • Nature
1 Citations

AlphaFold Accelerates Artificial Intelligence Powered Drug Discovery: Efficient Discovery of a Novel Cyclin-dependent Kinase 20 (CDK20) Small Molecule Inhibitor

This work successfully applied AlphaFold in their end-to-end AI-powered drug discovery engines constituted of a biocomputational platform PandaOmics and a generative chemistry platform Chemistry42, to identify a first-in-class hit molecule of a novel target without an experimental structure starting from target selection towards hit identification in a costand time-efficient manner.