The science and therapy of glucocorticoid-induced bone loss.

  title={The science and therapy of glucocorticoid-induced bone loss.},
  author={Nancy E. Lane and Barbara P. Lukert},
  journal={Endocrinology and metabolism clinics of North America},
  volume={27 2},
Glucocorticoids are critical in the management of chronic, noninfectious, inflammatory diseases. Bone loss is a most devastating side effect of these powerful medications. Glucocorticoids produce bone loss by altering calcium metabolism, suppressing gonadal hormone production, and inhibiting bone formation. Now that the mechanism of glucocorticoid-induced bone loss is understood and effective medications are available, this disease can be prevented and reversed. 

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